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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3359 | Aprotinin | Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin | Others , Serine Protease , Influenza Virus , Proteasome |
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat... | |||
T76240 | Urinary Trypsin Inhibitor Fragment | ||
Urinary Trypsin Inhibitor Fragment, a proteolytically derived segment of urinary trypsin inhibitor, demonstrates the capability to inhibit tumor cell invasion through limited proteolysis [1]. | |||
T8362 | Benzamidine hydrochloride | Benzamidine HCl | Serine/threonin kinase , Serine Protease |
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively). | |||
T17011 | TCH-165 | Proteasome | |
TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs. | |||
T8802 | 2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- | 2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur | Serine Protease |
2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine or synthetically produced. | |||
T30519 | BMS-363131 | BMS363131,BMS 363131 | Serine Protease |
BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM. | |||
TN1372 | Alpha-Amyrin | alpha-Amyrenol,α-Amyrin,alpha-Amyrine,Viminalol | P450 , Serine Protease , ROS |
Alpha-Amyrin (alpha-Amyrine) is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory. | |||
T6370 | AEBSF hydrochloride | AEBSF HCl,Pefabloc SC | Thrombin , Serine Protease , Influenza Virus |
AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin. | |||
T16169 | N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride | N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride | Others , Proteasome , COX |
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhib... | |||
T60248 | 4-Aminobenzamidine dihydrochloride | p-Aminobenzamidine dihydrochloride | Serine Protease |
4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inh... | |||
T6941 | PI-1840 | PI 1840 | PARP , Proteasome |
PI-1840(IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L). | |||
T16012 | Marizomib | NPI-0052,Salinosporamide A,ML858 | Proteasome |
Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectiv... | |||
T2391 | Camostat mesylate | FOY-S980,FOY305,Camostat mesilate | Serine/threonin kinase , SARS-CoV , Sodium Channel |
Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function. | |||
T7016 | VR23 | Apoptosis , Proteasome , Caspase | |
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes. | |||
T9670L | Patamostat HCl | Patamostat HCl(114568-26-2 Free base) | Serine Protease , Protease |
Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50 values of 39 nM, 950 nM, and 1.9 μM, respectively.Patamosta... | |||
T2122 | Ixazomib | MLN2238 | Proteasome , Caspase , Autophagy |
Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also i... | |||
T67959 | Pirodomast | Thrombin , Serine Protease | |
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas... | |||
T30510 | BMS-262084 | BMS 262084,I0IR71971G,UNII-I0IR71971G,CHEMBL71037 | |
BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma. | |||
T29969 | AMG-126737 | 105RSZ5CNS,AMG 126737,SCHEMBL7986111 | |
AMG-126737 is an effective human lung mast cell trypsin inhibitor with potential therapeutic effect in lung diseases. | |||
T62464 | Bz-D-Arg-pNA hydrochloride | ||
Bz-D-Arg-pNA hydrochloride is a competitive trypsin inhibitor. |